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研究業績

原著論文

  1. Takeuchi H*, Nagahara S
    “Development of a versatile system to facilitate targeted knockout/elimination using CRISPR/Cas9 for highly duplicated gene families in Arabidopsis sexual reproduction”
    bioRxiv, preprint (2024)
    https://doi.org/10.1101/2024.04.22.590670
  2. Takeuchi H*, Nagahara S, Higashiyama T, Berger F
    “The chaperone NASP contributes to de novo deposition of the centromeric histone variant CENH3 in Arabidopsis early embryogenesis”
    Plant and Cell Physiology, Vol. 65, pp1135-1148 (2024)
    https://doi.org/10.1093/pcp/pcae030
    プレスリリース(名古屋大学ITbM
  3. Ferreira MJ, Silva J, Takeuchi H, Suzuki T, Higashiyama T, Coimbra S*
    “Transcriptomic landscape of seedstick in Arabidopsis thaliana funiculus after fertilisation”
    BMC Plant Biology, Vol. 24, 771 (2024)
    https://doi.org/10.1186/s12870-024-05489-4
  4. Susaki D, Izumi R, Oi T, Takeuchi H, Shin JM, Sugi N, Kinoshita T, Higashiyama T, Kawashima T, Maruyama D*
    “F-actin regulates polarized secretion of pollen tube attractants in Arabidopsis synergid cell”
    Plant Cell, vol. 35, pp1222-1240 (2023)
    https://doi.org/10.1093/plcell/koac371
    プレスリリース(横浜市立大学)
  5. Nagae TT, Takeuchi H, Higashiyama T*
    “Quantification of species-preferential micropylar chemoattraction in Arabidopsis by fluorescein diacetate staining of pollen tubes”
    International Journal of Molecular Sciences, vol. 23, 2722 (2022)
    https://doi.org/10.3390/ijms23052722
  6. Motomura K, Takeuchi H, Notaguchi M, Tsuchi H, Takeda A, Kinoshita T, Higashiyama T, Maruyama D*
    “Persistent directional growth capability in Arabidopsis thaliana pollen tubes after nuclear elimination from the apex”
    Nature Communications, vol. 12, 2331 (2021)
    https://doi.org/10.1038/s41467-021-22661-8
    プレスリリース(横浜市立大学)
  7. Nagahara S*, Takeuchi H, Higashiyama T*
    “Polyspermy block in the central cell during double fertilization of Arabidopsis thaliana
    Frontiers in Plant Science, vol. 11, 588700 (2021)
    https://doi.org/10.3389/fpls.2020.588700
  8. Komaki S, Takeuchi H, Hamamura Y, Heese M, Hashimoto T, Schnittger A*
    “Functional analysis of the chromosomal passenger complex”
    Plant Physiology, vol. 183, pp1586-1599 (2020)
    https://doi.org/10.1104/pp.20.00344
  9. Motomura K, Arae T, Araki-Uramoto H, Suzuki Y, Takeuchi H, Suzuki T, Ichihashi Y, Shibata A, Shirasu K, Takeda A, Higashiyama T, Chiba Y*
    “AtNOT1 is a novel regulator of gene expression during pollen development”
    Plant and Cell Physiology, vol. 61, pp712-721 (2020)
    https://doi.org/10.1093/pcp/pcz235
  10. Zhang X, Liu W, Nagae TT, Takeuchi H, Zhang H, Han Z, Higashiyama T*, Chai J*
    “Structural basis for receptor recognition of pollen tube attraction peptides”
    Nature Communications, vol. 8, 1331 (2017)
    https://doi.org/10.1038/s41467-017-01323-8
    プレスリリース(名古屋大学)
  11. Wollmann H, Stroud H, Yelagandula R, Tarutani Y, Jiang D, Jing L, Jamge B, Takeuchi H, Holec S, Nie X, Kakutani T, Jacobsen SE*, Berger F*
    “The histone H3 variant H3.3 regulates gene body DNA methylation in Arabidopsis thaliana
    Genome Biology, vol. 18, 94 (2017)
    https://doi.org/10.1186/s13059-017-1221-3
  12. Takeuchi H*(co-corresponding author), Higashiyama T*
    “Tip-localized receptors control pollen tube growth and LURE sensing in Arabidopsis
    Nature, vol. 531, pp245-248 (2016)
    https://doi.org/10.1038/nature17413
    プレスリリース(名古屋大学) Nature | News & Views 日本語の解説論文
  13. Maruyama D*, Völz R, Takeuchi H, Mori T, Igawa T, Kurihara D, Kawashima T, Ueda M, Ito M, Umeda M, Nishikawa S, Groß-Hardt R, Higashiyama T
    “Rapid elimination of the persistent synergid through a cell fusion mechanism”
    Cell, vol. 161, pp907-918 (2015)
    https://doi.org/10.1016/j.cell.2015.03.018
    プレスリリース(名古屋大学)
  14. Susaki D, Takeuchi H, Tsutsui H, Kurihara D, Higashiyama T*
    “Live imaging and laser disruption reveal the dynamics and cell-cell communication during Torenia fournieri female gametophyte development”
    Plant and Cell Physiology, vol. 56, pp1031-1041 (2015)
    https://doi.org/10.1093/pcp/pcv031
  15. Nagahara S, Takeuchi H, Higashiyama T*
    “Generation of a homozygous fertilization-defective gcs1 mutant by heat-inducible removal of a rescue gene”
    Plant Reproduction, vol. 28, pp33-46 (2015)
    https://doi.org/10.1007/s00497-015-0256-4
  16. Hamamura Y, Nishimaki M, Takeuchi H, Geitmann A, Kurihara D, Higashiyama T*
    “Live imaging of calcium spikes during double fertilization in Arabidopsis
    Nature Communications, vol. 5, 4722 (2014)
    https://doi.org/10.1038/ncomms5722
  17. Maruyama D, Hamamura Y, Takeuchi H, Susaki D, Nishimaki M, Kurihara D, Kasahara RD, Higashiyama T*
    “Independent control by each female gamete prevents the attraction of multiple pollen tubes”
    Developmental Cell, vol. 25, pp317-323 (2013)
    https://doi.org/10.1016/j.devcel.2013.03.013
  18. Takeuchi H, Higashiyama T*
    “A species-specific cluster of defensin-like genes encodes diffusible pollen tube attractants in Arabidopsis
    PLoS Biology, vol. 10, e1001449 (2012)
    https://doi.org/10.1371/journal.pbio.1001449
    プレスリリース(名古屋大学)
  19. Okuda S, Tsutsui H, Shiina K, Sprunck S, Takeuchi H, Yui R, Kasahara RD, Hamamura Y, Mizukami A, Susaki D, Kawano N, Sakakibara T, Namiki S, Itoh K, Otsuka K, Matsuzaki M, Nozaki H, Kuroiwa T, Nakano A, Kanaoka MM, Dresselhaus T, Sasaki N, Higashiyama T*
    “Defensin-like polypeptide LUREs are pollen tube attractants secreted from synergid cells”
    Nature, vol. 458, pp357-361 (2009)
    https://doi.org/10.1038/nature07882
    プレスリリース(JST、名古屋大学)

英語総説

  1. Takeuchi H*
    “The role of diverse LURE-type cysteine-rich peptides as signaling molecules in plant reproduction”
    Peptides, Vol. 142, 170572 (2021)
    https://doi.org/10.1016/j.peptides.2021.170572
  2. Higashiyama T*, Takeuchi H
    “The mechanism and key molecules involved in pollen tube guidance”
    Annual Review of Plant Biology, Vol. 66, pp393-413 (2015)
    https://doi.org/10.1146/annurev-arplant-043014-115635
  3. Takeuchi H, Higashiyama T*
    “Attraction of tip-growing pollen tubes by the female gametophyte”
    Current Opinion in Plant Biology, Vol. 14, pp614-621 (2011)
    https://doi.org/10.1016/j.pbi.2011.07.010

日本語総説・解説

  1. 武内秀憲*, 東山哲也
    「シロイヌナズナにおいて花粉管の先端に局在する受容体が花粉管の伸長および花粉管誘引ペプチドの感知を制御する」
    ライフサイエンス新着論文レビュー (2016)
    https://doi.org/10.7875/first.author.2016.026
  2. 武内秀憲*, 東山哲也
    「シロイヌナズナの花粉管誘引物質LUREペプチド群の発見」
    植物の生長調節, 48巻, 73-78頁 (2013)
    https://doi.org/10.18978/jscrp.48.1_73
  3. 東山哲也*, 奥田哲弘, 筒井大貴, 椎名恵子, 武内秀憲, 金岡雅浩, 佐々木成江
    「花粉管誘引物質ルアーの発見」
    化学と生物, 47巻, 617-623頁 (2009)
    https://doi.org/10.1271/kagakutoseibutsu.47.617

学会発表など

学会発表、招待講演、特許、研究費獲得実績、その他の活動などについては以下のリンクからご覧ください

東京大学大学院 総合文化研究科

植物生殖進化遺伝学 武内研究室

〒153-8902 東京都目黒区駒場3-8-1
東京大学大学院総合文化研究科16号館627/628A号室

Takeuchi Laboratory
Evolution and Genetics of Plant Reproduction

Graduate School of Arts and Sciences
The University of Tokyo

Komaba-I Campus Building 16-627/628A
Graduate School of Arts and Sciences, The University of Tokyo
3-8-1 Komaba, Meguro, Tokyo 153-8902 JAPAN

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